Testosterone Replacement Therapy: Myths vs. Facts

Testosterone is the primary male sex hormone responsible for muscle mass, energy, libido, and overall vitality. As men age, testosterone levels naturally decline. However, in some men, this drop is more significant and can lead to a condition known as male hypogonadism. For those affected, testosterone replacement therapy (TRT) can be a game-changer—yet, it’s also surrounded by misinformation.

At Twenty One Medical, a trusted Men’s Health Clinic in Pineville, we believe in educating our patients with facts, not fear. Let’s explore the most common myths about men’s testosterone therapy and replace them with the truth.

Myth #1: TRT Is Only for Older Men

Fact: While testosterone levels often decline with age, male hypogonadism can affect younger men too. Low testosterone may result from medical conditions, injuries, or hormonal imbalances, regardless of age. Men’s testosterone therapy is prescribed based on symptoms and lab results—not just age.

Myth #2: Low Testosterone Is Just a Natural Part of Aging—You Have to Live With It

Fact: While it's normal for testosterone to decline slightly over time, a significant drop that affects your quality of life should not be ignored. Common symptoms include fatigue, low libido, depression, weight gain, and reduced muscle mass. These aren’t just inconveniences—they're signals that your body might need help. That’s where a men’s health clinic can step in to evaluate and recommend the right course of action.

Myth #3: TRT Causes Prostate Cancer

Fact: This is one of the most persistent myths about testosterone replacement therapy. However, multiple modern studies have found no direct link between TRT and an increased risk of prostate cancer. In fact, low testosterone itself may be associated with more aggressive forms of cancer. That said, men with a history of prostate issues are thoroughly screened before starting therapy to ensure safety.

Myth #4: Men’s Testosterone Therapy Is Only About Sex Drive

Fact: While TRT can help improve libido, its benefits extend well beyond sexual health. Testosterone replacement therapy may also enhance energy, cognitive function, mood, muscle strength, and bone density. At our men’s health clinic, we treat the whole person—not just a symptom.

Myth #5: Over-the-Counter Testosterone Boosters Are Just as Effective

Fact: Most supplements marketed as “testosterone boosters” lack scientific evidence and are not FDA-approved. They often contain herbal ingredients with minimal hormonal impact. On the other hand, medical testosterone therapy is prescribed based on lab work and monitored closely for safety and effectiveness. For men with male hypogonadism, these over-the-counter products are no substitute for real medical care.

Myth #6: TRT Will Make You Aggressive or Cause 'Roid Rage'

Fact: This stereotype comes from abuse of anabolic steroids, not medically supervised TRT. In reality, testosterone replacement therapy aims to restore normal levels, not create excessive ones. When managed by experienced providers, TRT is not associated with aggressive behavior. In fact, many men report feeling more emotionally balanced after treatment.

Myth #7: Once You Start TRT, You Can’t Stop

Fact: While TRT is often a long-term solution for chronic low testosterone, it is not irreversible. Some men may choose to stop therapy or explore alternative treatments. However, stopping TRT without medical guidance can lead to a return of symptoms. It’s important to work with a knowledgeable provider who can help you taper safely if needed.

How a Men’s Health Clinic Can Help

At Twenty One Medical, we offer tailored solutions for men facing hormonal issues like male hypogonadism. Our approach includes:

• Thorough blood testing to confirm low testosterone

• Personalized treatment plans using topical, injectable, or pellet-based testosterone replacement therapy

• Ongoing monitoring to ensure optimal results and safety

Whether you're experiencing mood swings, decreased stamina, or reduced sexual health, our men’s health clinic can help you reclaim your vitality through trusted, evidence-based care.

Final Thoughts

There’s a lot of noise out there about testosterone replacement therapy, but separating myths from facts is key to making informed decisions. Men’s testosterone therapy is not about vanity—it’s about restoring balance, health, and confidence for those genuinely affected by male hypogonadism.

If you're feeling the signs of low testosterone, don’t let misinformation keep you from seeking help. Visit our Men’s Health Services page to learn how Twenty One Medical can support your health journey.